Advice Needed - 6 Team with heavy defence

Draft rookie here. Joined a 6 team PPR league with the following:

2 QB, 2 RB, 2 WR, 2 TE, 2 WR/RB/TE, 2 DST, 2 K, 2 DL, 2 LB, 2 DB, 2 IDP, 12 BN
4 QB max

Which round would you start drafting defensive players?