Defense vs other positions on your lineup?

This may be a dumb question. But I’ve heard different answers on it. Is it bad to play a defense that is on the other side of the ball to another player in your line-up? For example:
I have Dalvin Cook and the Eagles Defense in week 6. Seems to me to be a bad move. If Dalvin cook does good that will hurt the score of the Eagles D right?

I wouldnt look that far into it. Yes, if Dalvin cook has a monster game then thats not good for the Eagles. But generally its going to come down to sack, TOs, and special teams. That being said, I dont think the Eagles are a great play right now. I would find another DST off waivers.

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