Even though it’s 2QB, there’s still only going to be 24 guys off the board. And it sounds like they’re all kept pre-draft – as in: they’re not kept in place of a pick in the draft. That being the case, you’re simply worried about value and scarcity. Get the highest rated guys that are also from the most scarce positions.
What draft pick number will you have? That’ll determine who you’ll likely get with your first few picks and better inform who you should keep. As part of that, I’d go through your league’s other 11 rosters and do a best-bet on each of their 2 keepers. Most teams it’ll be pretty obvious. That list of 22 kept players will likely give you a clear picture of which 2 guys you’ll have to keep. Especially if you have a late 1st round pick, meaning you’ll have little chance of getting your 3rd best option during the draft’s first round.