Kyler in week 1

The Kyler breakout is real but in week 1 he plays the 49ers D. In a dynasty league I also have Matthew Stafford playing the Bears. Is it insane to sit Murray playing a tough 49er D.?

I mean it’s understandable but at the same time Murray was good last season versus the 49ers. Not saying that will transition to the same thing this year but they did have issues when facing mobile QBs last year