Line-up help due to McKinnon

With Mckinnon going down, i had to move chris carson to my RB2 spot behind melvin gordon. My flex is now open and i have to choose between Matt Breida, jordy nelson, Bilal Powell, or Tyler Lockett. I have kerryon as well. Its a 12 team ppr… 2WR, 2RB and 1FLEX. Any insight would be fantastic :smiley: