Line-Up Help // PPR

Hello all. I’m in dire need of line-up advice. Currently in 1st place in my league, and I want to keep it that way. Unfortunately this week and next week are when my options are most heavily affected by BYEs, and I just so happen to be playing the guy that’s in 2nd place.

Also, I’ll mention that I’m 6-2, and so are the next three guys that are projected in the playoff bracket. I have the most points scored, which is why I’m ahold of the top spot.

My Roster:

QB: Alex Smith, Phillip Rivers (BYE)
RB: LeVeon Bell (BYE), Kareem Hunt, Jordan Howard (BYE), Alvin Kamara, Joe Mixon
WR: AJ Green, Michael Thomas, Tyreek Hill, Golden Tate
TE: Hunter Henry, Austin Seferian-Jenkins
D/ST: Seahawks
K: Harrison Butker

Current Line-Up:
QB: Alex Smith
RB1: Kareem Hunt
RB2: Alvin Kamara
WR1: AJ Green
WR2: Michael Thomas
TE: Austin Seferian-Jenkins
D/ST: Seahawks
K: Harrison Butker

Do I start Mixon? Sit AJ and start Tate?

I know it’s important to consider the opponents line-up when setting your own. I’m facing a three-headed RB beast (Shady McCoy, Todd Gurley, Leonard Fournette), Brees at QB, Evan Engram at TE… He’s starting Sammy Watkins and Devante Parker, neither of whom scare me. Do I go conservative and start my upside studs? Play it safe and go match-up based?

Bump bump bump.