Need Help-Pick 2 Rb's and explain why

Kareem Hunt vs LA Chargers
Demarco Murray vs SF 49ers
CJ Anderson vs Ind. Colts
Giovani Bernard vs Minn. Vikings (Assuming Mixon sits out)

Thanks

hunt cause he is back and chargers that is there weak spot, run
CJ Anderson because new offensive coach seems to prefer him and it is clear last two weeks

murray is garbage and SF playing way better and at home
Gio playing super tough Minn who should bounce back