New to Keepers, Need help ASAP

Hey ya’ll could use some advice. Joining a STD scoring 2-keepers league which I’m new to. I will get Juju and Mike Evans locked in the 3rd and 4th. My question is considering majority of the top running back options will be kept from last year (some of which were picked in later rounds), how strongly should I consider a zero-RB strategy and try and grab another top WR and a TE for the first few rounds as many of the few remaining options have considerable question marks for RD 1/2 (i.e. Todd Gurley, Zeke).