Playing a DST against your star players

This week I have David Johnson as my RB1 but my defence is the LA Chargers. Obviously the Chargers are a good play this week and DJ is my number 1 RB so has to play, but what are people’s views on playing a defence that’s facing your star player? Feels a bit counter productive to me, but im not really sure what to do.

For context, i’m in a 12 team 0.5 PPR league & I can pick up and play either the Cowboys or Patriots instead but would be dropping the Chargers to the waiver as no one on my bench is worth dropping for a DST stash…