Playoff add/drops

Starting to look like I’m playoff bound in my medium-money, high-bragging-rights league. No PPR, 2 WR 2 RB 1 FLX. Do I drop anyone to pick up handcuffs or surplus defenses?
QB: Wentz
RB: CMC, Dalvin, Lindsay
WR: Keenan Allen, Alan Robinson, Parker, DJ Moore, Juju, Woods, Sutton, Gordon
TE: Henry, Cook
DEF: Saints