Start/Sit Pick 2 RBs and a Flex

My running back options are Jay Ajayi, Alex Collins, Alfred Morris, Darren Mcfadden, and Bilal Powell. For my flex spot it’s any of the above running backs or Ted Ginn. I’m leaning towards starting Collins, Morris, and Powell. Is this good or should I make a change?

Any advice, I’m not sure what to do.