When to Handcuff

I usually never worry about handcuffing my RBs and it hasn’t got me into any trouble, but with all the injuries in today’s game I think I’ve just been lucky. I have Melvin Gordon in a 14 team league with only 5 bench spots. After seeing the Austin Eckler/Melvin Gordon performances against KC I’m wondering if he is worth any of my FAAB. Any advice on this situation or handcuffing in general?